A New and Efficient Synthesis of 6-O-Methylscutellarein, the Major Metabolite of the Natural Medicine Scutellarin

In this paper, a new and efficient synthesis of 6-O-methylscutellarein (3), the major metabolite of the natural medicine scutellarin, is reported. Two hydroxyl groups at C-4′ and C-7 in 2 were selectively protected by chloromethyl methyl ether after the reaction conditions were optimized, then 6-O-m...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Dong, Ze-Xi, Gu, Ting, Li, Nian-Guang, Zhang, Peng-Xuan, Wu, Wen-Yu, Yu, Shao-Peng, Tang, Yu-Ping, Yang, Jian-Ping, Shi, Zhi-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272442/
https://www.ncbi.nlm.nih.gov/pubmed/26042857
http://dx.doi.org/10.3390/molecules200610184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272442/
https://www.ncbi.nlm.nih.gov/pubmed/26042857
http://dx.doi.org/10.3390/molecules200610184

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