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Characterization at 25 °C of Sodium Hyaluronate in Aqueous Solutions Obtained by Transport Techniques

Mutual diffusion coefficients, D, were determined for aqueous solutions of sodium hyaluronate (NaHy) at 25 °C and concentrations ranging from 0.00 to 1.00 g·dm(−3) using the Taylor dispersion technique. From these experimental data, it was possible to estimate some parameters, such as the hydrodynam...

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Detalles Bibliográficos
Autores principales: Mráček, Aleš, Gřundělová, Lenka, Minařík, Antonín, Veríssimo, Luís M. P., Barros, Marisa C. F., Ribeiro, Ana C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272485/
https://www.ncbi.nlm.nih.gov/pubmed/25849804
http://dx.doi.org/10.3390/molecules20045812
Descripción
Sumario:Mutual diffusion coefficients, D, were determined for aqueous solutions of sodium hyaluronate (NaHy) at 25 °C and concentrations ranging from 0.00 to 1.00 g·dm(−3) using the Taylor dispersion technique. From these experimental data, it was possible to estimate some parameters, such as the hydrodynamic radius R(h), and the diffusion coefficient at infinitesimal concentration, D(0), of hyaluronate ion, permitting us to have a better understanding of the structure of these systems of sodium hyaluronate in aqueous solutions. The additional viscosity measurements were done and Huggins constant, k(H), and limiting viscosity number, [η], were computed for interaction NaHy/water and NaHy/NaHy determination.