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Rational Drug Design and Synthesis of Molecules Targeting the Angiotensin II Type 1 and Type 2 Receptors

The angiotensin II (Ang II) type 1 and type 2 receptors (AT(1)R and AT(2)R) orchestrate an array of biological processes that regulate human health. Aberrant function of these receptors triggers pathophysiological responses that can ultimately lead to death. Therefore, it is important to design and...

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Detalles Bibliográficos
Autores principales: Kellici, Tahsin F., Tzakos, Andreas G., Mavromoustakos, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272512/
https://www.ncbi.nlm.nih.gov/pubmed/25738535
http://dx.doi.org/10.3390/molecules20033868