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Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters
The stoichiometric use of hydrogen peroxide in the presence of a selenium-containing catalyst in water is here reported as a new ecofriendly protocol for the synthesis of variously functionalized carboxylic acids and esters. The method affords the desired products in good to excellent yields under v...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272575/ https://www.ncbi.nlm.nih.gov/pubmed/26060915 http://dx.doi.org/10.3390/molecules200610496 |
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author | Sancineto, Luca Tidei, Caterina Bagnoli, Luana Marini, Francesca Lenardão, Eder J. Santi, Claudio |
author_facet | Sancineto, Luca Tidei, Caterina Bagnoli, Luana Marini, Francesca Lenardão, Eder J. Santi, Claudio |
author_sort | Sancineto, Luca |
collection | PubMed |
description | The stoichiometric use of hydrogen peroxide in the presence of a selenium-containing catalyst in water is here reported as a new ecofriendly protocol for the synthesis of variously functionalized carboxylic acids and esters. The method affords the desired products in good to excellent yields under very mild conditions starting directly from commercially available aldehydes. Using benzaldehyde as a prototype the gram scale synthesis of benzoic acid is described, in which the aqueous medium and the catalyst could be recycled at last five times while achieving an 87% overall yield. |
format | Online Article Text |
id | pubmed-6272575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62725752018-12-31 Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters Sancineto, Luca Tidei, Caterina Bagnoli, Luana Marini, Francesca Lenardão, Eder J. Santi, Claudio Molecules Article The stoichiometric use of hydrogen peroxide in the presence of a selenium-containing catalyst in water is here reported as a new ecofriendly protocol for the synthesis of variously functionalized carboxylic acids and esters. The method affords the desired products in good to excellent yields under very mild conditions starting directly from commercially available aldehydes. Using benzaldehyde as a prototype the gram scale synthesis of benzoic acid is described, in which the aqueous medium and the catalyst could be recycled at last five times while achieving an 87% overall yield. MDPI 2015-06-08 /pmc/articles/PMC6272575/ /pubmed/26060915 http://dx.doi.org/10.3390/molecules200610496 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sancineto, Luca Tidei, Caterina Bagnoli, Luana Marini, Francesca Lenardão, Eder J. Santi, Claudio Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters |
title | Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters |
title_full | Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters |
title_fullStr | Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters |
title_full_unstemmed | Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters |
title_short | Selenium Catalyzed Oxidation of Aldehydes: Green Synthesis of Carboxylic Acids and Esters |
title_sort | selenium catalyzed oxidation of aldehydes: green synthesis of carboxylic acids and esters |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272575/ https://www.ncbi.nlm.nih.gov/pubmed/26060915 http://dx.doi.org/10.3390/molecules200610496 |
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