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Synthesis and Anti-Trypanosoma cruzi Activity of Diaryldiazepines

Chagas disease is a so-called “neglected disease” and endemic to Latin America. Nifurtimox and benznidazole are drugs that have considerable efficacy in the treatment of the acute phase of the disease but cause many significant side effects. Furthermore, in the Chronic Phase its efficiency is reduce...

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Detalles Bibliográficos
Autores principales: Menezes, Júlio César L., Vaz, Luana Beatriz A., Vieira, Paula Melo de Abreu, Fonseca, Kátia da Silva, Carneiro, Cláudia Martins, Taylor, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272580/
https://www.ncbi.nlm.nih.gov/pubmed/25546620
http://dx.doi.org/10.3390/molecules20010043