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NKCS, a Mutant of the NK-2 Peptide, Causes Severe Distortions and Perforations in Bacterial, But Not Human Model Lipid Membranes
NKCS is an improved mutant of the bioactive peptide NK-2, which shows strong activity against Escherichia coli and low toxicity towards human cells. The different activity demonstrates the relevance of the physico-chemical nature of the target membrane for the biological effect of this peptide. We s...
Autores principales: | Ciobanasu, Corina, Rzeszutek, Agnieszka, Kubitscheck, Ulrich, Willumeit, Regine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272639/ https://www.ncbi.nlm.nih.gov/pubmed/25913932 http://dx.doi.org/10.3390/molecules20046941 |
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