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Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus

Leojaponin (2), a labdane diterpene, was isolated from the EtOH extract of the herb of Leonurus japonicus together with a new halimane diterpene named isoleojaponin (1). Isoleojaponin has a new diterpene skeleton with a unique cross-conjugated α,β-unsaturated ketone system, Their structures were elu...

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Detalles Bibliográficos
Autores principales: Wu, Hankui, Wang, Sensheng, Xu, Zhiyong, Sun, Shanshan, Liu, Haijuan, Wang, Jinjin, E, Yan, Lv, Yanyan, Dong, Xuelin, Li, Gang, Zhang, Liping, Shi, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272656/
https://www.ncbi.nlm.nih.gov/pubmed/25574824
http://dx.doi.org/10.3390/molecules20010839
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author Wu, Hankui
Wang, Sensheng
Xu, Zhiyong
Sun, Shanshan
Liu, Haijuan
Wang, Jinjin
E, Yan
Lv, Yanyan
Dong, Xuelin
Li, Gang
Zhang, Liping
Shi, Yunfeng
author_facet Wu, Hankui
Wang, Sensheng
Xu, Zhiyong
Sun, Shanshan
Liu, Haijuan
Wang, Jinjin
E, Yan
Lv, Yanyan
Dong, Xuelin
Li, Gang
Zhang, Liping
Shi, Yunfeng
author_sort Wu, Hankui
collection PubMed
description Leojaponin (2), a labdane diterpene, was isolated from the EtOH extract of the herb of Leonurus japonicus together with a new halimane diterpene named isoleojaponin (1). Isoleojaponin has a new diterpene skeleton with a unique cross-conjugated α,β-unsaturated ketone system, Their structures were elucidated by physical and spectroscopic analysis, and the relative configuration of the chiral C-9 carbon was determined by a computational method, and analysis of its possible biogenesis pathways.
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spelling pubmed-62726562018-12-28 Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus Wu, Hankui Wang, Sensheng Xu, Zhiyong Sun, Shanshan Liu, Haijuan Wang, Jinjin E, Yan Lv, Yanyan Dong, Xuelin Li, Gang Zhang, Liping Shi, Yunfeng Molecules Communication Leojaponin (2), a labdane diterpene, was isolated from the EtOH extract of the herb of Leonurus japonicus together with a new halimane diterpene named isoleojaponin (1). Isoleojaponin has a new diterpene skeleton with a unique cross-conjugated α,β-unsaturated ketone system, Their structures were elucidated by physical and spectroscopic analysis, and the relative configuration of the chiral C-9 carbon was determined by a computational method, and analysis of its possible biogenesis pathways. MDPI 2015-01-07 /pmc/articles/PMC6272656/ /pubmed/25574824 http://dx.doi.org/10.3390/molecules20010839 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Wu, Hankui
Wang, Sensheng
Xu, Zhiyong
Sun, Shanshan
Liu, Haijuan
Wang, Jinjin
E, Yan
Lv, Yanyan
Dong, Xuelin
Li, Gang
Zhang, Liping
Shi, Yunfeng
Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus
title Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus
title_full Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus
title_fullStr Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus
title_full_unstemmed Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus
title_short Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus
title_sort isoleojaponin, a new halimane diterpene isolated from leonurus japonicus
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272656/
https://www.ncbi.nlm.nih.gov/pubmed/25574824
http://dx.doi.org/10.3390/molecules20010839
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