Synthesis of C-Arylnucleoside Analogues

Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies...

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Detalles Bibliográficos
Autores principales: Len, Christophe, Enderlin, Gérald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272657/
https://www.ncbi.nlm.nih.gov/pubmed/25793544
http://dx.doi.org/10.3390/molecules20034967
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author Len, Christophe
Enderlin, Gérald
author_facet Len, Christophe
Enderlin, Gérald
author_sort Len, Christophe
collection PubMed
description Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review.
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spelling pubmed-62726572018-12-31 Synthesis of C-Arylnucleoside Analogues Len, Christophe Enderlin, Gérald Molecules Review Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review. MDPI 2015-03-18 /pmc/articles/PMC6272657/ /pubmed/25793544 http://dx.doi.org/10.3390/molecules20034967 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Len, Christophe
Enderlin, Gérald
Synthesis of C-Arylnucleoside Analogues
title Synthesis of C-Arylnucleoside Analogues
title_full Synthesis of C-Arylnucleoside Analogues
title_fullStr Synthesis of C-Arylnucleoside Analogues
title_full_unstemmed Synthesis of C-Arylnucleoside Analogues
title_short Synthesis of C-Arylnucleoside Analogues
title_sort synthesis of c-arylnucleoside analogues
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272657/
https://www.ncbi.nlm.nih.gov/pubmed/25793544
http://dx.doi.org/10.3390/molecules20034967
work_keys_str_mv AT lenchristophe synthesisofcarylnucleosideanalogues
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