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Targeting Carbonic Anhydrase IX Activity and Expression

Metastatic tumors are often hypoxic exhibiting a decrease in extracellular pH (~6.5) due to a metabolic transition described by the Warburg Effect. This shift in tumor cell metabolism alters the tumor milieu inducing tumor cell proliferation, angiogenesis, cell motility, invasiveness, and often resi...

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Detalles Bibliográficos
Autores principales:	Mahon, Brian P., Pinard, Melissa A., McKenna, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272707/ https://www.ncbi.nlm.nih.gov/pubmed/25647573 http://dx.doi.org/10.3390/molecules20022323

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