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Synthesis of 5-Alkoxythieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine Derivatives and Evaluation of Their Anticonvulsant Activities

This work concerns the design and synthesis of novel, substituted 5-alkoxythieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine derivatives 5a–p prepared from 3-amino-2-thiophenecarboxylic acid methyl ester. The final compounds were screened for their in vivo anticonvulsant activity using maximal electrosho...

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Detalles Bibliográficos
Autores principales: Wang, Shi-Ben, Piao, Guang-Chun, Zhang, Hong-Jian, Quan, Zhe-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272708/
https://www.ncbi.nlm.nih.gov/pubmed/25884556
http://dx.doi.org/10.3390/molecules20046827