Synthesis, Central Nervous System Activity and Structure-Activity Relationships of Novel 1-(1-Alkyl-4-aryl-4,5-dihydro-1H-imidazo)-3-substituted Urea Derivatives

A series of 10 novel urea derivatives has been synthesized and evaluated for their central nervous system activity. Compounds 3a–3h were prepared in the reaction between the respective 1-alkyl-4-aryl-4,5-dihydro-1H-imidazol-2-amines 1a and 1b and appropriate benzyl-, phenethyl-isocyanate or ethyl 4-...

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Detalles Bibliográficos
Autores principales: Szacoń, Elżbieta, Rządkowska, Marzena, Kaczor, Agnieszka A., Kędzierska, Ewa, Fidecka, Sylwia, Matosiuk, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272709/
https://www.ncbi.nlm.nih.gov/pubmed/25730390
http://dx.doi.org/10.3390/molecules20033821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272709/
https://www.ncbi.nlm.nih.gov/pubmed/25730390
http://dx.doi.org/10.3390/molecules20033821

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