Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)

The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene. Other coumarins such as 7-methoxy-8-(2-formyl-2-methylpropyl) coumarin and osthol...

Descripción completa

Detalles Bibliográficos
Autores principales: Autore, Giuseppina, Marzocco, Stefania, Formisano, Carmen, Bruno, Maurizio, Rosselli, Sergio, Jemia, Mariem Ben, Senatore, Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272710/
https://www.ncbi.nlm.nih.gov/pubmed/25603502
http://dx.doi.org/10.3390/molecules20011571
_version_ 1783377220228612096
author Autore, Giuseppina
Marzocco, Stefania
Formisano, Carmen
Bruno, Maurizio
Rosselli, Sergio
Jemia, Mariem Ben
Senatore, Felice
author_facet Autore, Giuseppina
Marzocco, Stefania
Formisano, Carmen
Bruno, Maurizio
Rosselli, Sergio
Jemia, Mariem Ben
Senatore, Felice
author_sort Autore, Giuseppina
collection PubMed
description The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene. Other coumarins such as 7-methoxy-8-(2-formyl-2-methylpropyl) coumarin and osthole also occurred. The antiproliferative activity of Magydaris tomentosa flower extract has been evaluated in vitro on murine monocye/macrophages (J774A.1), human melanoma (A375) and human breast cancer (MCF-7) tumor cell lines, showing a major activity against the latter.
format Online
Article
Text
id pubmed-6272710
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62727102018-12-28 Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae) Autore, Giuseppina Marzocco, Stefania Formisano, Carmen Bruno, Maurizio Rosselli, Sergio Jemia, Mariem Ben Senatore, Felice Molecules Article The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene. Other coumarins such as 7-methoxy-8-(2-formyl-2-methylpropyl) coumarin and osthole also occurred. The antiproliferative activity of Magydaris tomentosa flower extract has been evaluated in vitro on murine monocye/macrophages (J774A.1), human melanoma (A375) and human breast cancer (MCF-7) tumor cell lines, showing a major activity against the latter. MDPI 2015-01-16 /pmc/articles/PMC6272710/ /pubmed/25603502 http://dx.doi.org/10.3390/molecules20011571 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Autore, Giuseppina
Marzocco, Stefania
Formisano, Carmen
Bruno, Maurizio
Rosselli, Sergio
Jemia, Mariem Ben
Senatore, Felice
Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)
title Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)
title_full Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)
title_fullStr Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)
title_full_unstemmed Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)
title_short Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)
title_sort cytotoxic activity and composition of petroleum ether extract from magydaris tomentosa (desf.) w. d. j. koch (apiaceae)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272710/
https://www.ncbi.nlm.nih.gov/pubmed/25603502
http://dx.doi.org/10.3390/molecules20011571
work_keys_str_mv AT autoregiuseppina cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae
AT marzoccostefania cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae
AT formisanocarmen cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae
AT brunomaurizio cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae
AT rossellisergio cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae
AT jemiamariemben cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae
AT senatorefelice cytotoxicactivityandcompositionofpetroleumetherextractfrommagydaristomentosadesfwdjkochapiaceae

Ejemplares similares