iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)

An enantiomeric pair of new fatty acid-derived hydroxylated tetrahydrofurans, here named iso-petromyroxols, were isolated from sea lamprey larvae-conditioned water. The relative configuration of iso-petromyroxol was elucidated with 1D and 2D NMR spectroscopic analyses. The ratio of enantiomers (er)...

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Detalles Bibliográficos
Autores principales: Li, Ke, Brant, Cory O., Bussy, Ugo, Pinnamaneni, Harshita, Patel, Hinal, Hoye, Thomas R., Li, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272722/
https://www.ncbi.nlm.nih.gov/pubmed/25806547
http://dx.doi.org/10.3390/molecules20035215
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author Li, Ke
Brant, Cory O.
Bussy, Ugo
Pinnamaneni, Harshita
Patel, Hinal
Hoye, Thomas R.
Li, Weiming
author_facet Li, Ke
Brant, Cory O.
Bussy, Ugo
Pinnamaneni, Harshita
Patel, Hinal
Hoye, Thomas R.
Li, Weiming
author_sort Li, Ke
collection PubMed
description An enantiomeric pair of new fatty acid-derived hydroxylated tetrahydrofurans, here named iso-petromyroxols, were isolated from sea lamprey larvae-conditioned water. The relative configuration of iso-petromyroxol was elucidated with 1D and 2D NMR spectroscopic analyses. The ratio of enantiomers (er) in the natural sample was measured by chiral-HPLC-MS/MS to be ca. 3:1 of (–)- to (+)-antipodes.
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spelling pubmed-62727222018-12-31 iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus) Li, Ke Brant, Cory O. Bussy, Ugo Pinnamaneni, Harshita Patel, Hinal Hoye, Thomas R. Li, Weiming Molecules Article An enantiomeric pair of new fatty acid-derived hydroxylated tetrahydrofurans, here named iso-petromyroxols, were isolated from sea lamprey larvae-conditioned water. The relative configuration of iso-petromyroxol was elucidated with 1D and 2D NMR spectroscopic analyses. The ratio of enantiomers (er) in the natural sample was measured by chiral-HPLC-MS/MS to be ca. 3:1 of (–)- to (+)-antipodes. MDPI 2015-03-23 /pmc/articles/PMC6272722/ /pubmed/25806547 http://dx.doi.org/10.3390/molecules20035215 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Ke
Brant, Cory O.
Bussy, Ugo
Pinnamaneni, Harshita
Patel, Hinal
Hoye, Thomas R.
Li, Weiming
iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)
title iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)
title_full iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)
title_fullStr iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)
title_full_unstemmed iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)
title_short iso-Petromyroxols: Novel Dihydroxylated Tetrahydrofuran Enantiomers from Sea Lamprey (Petromyzon marinus)
title_sort iso-petromyroxols: novel dihydroxylated tetrahydrofuran enantiomers from sea lamprey (petromyzon marinus)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272722/
https://www.ncbi.nlm.nih.gov/pubmed/25806547
http://dx.doi.org/10.3390/molecules20035215
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