Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride

Pincer (Phebox)Ir(mesityl)(OAc) (2) (Phebox = 3,5-dimethylphenyl-2,6-bis(oxazolinyl)) complex, formed by benzylic C-H activation of mesitylene (1,3,5-trimethylbenzene) using (Phebox)Ir(OAc)(2)OH(2) (1), was treated with thionyl chloride to rapidly form 1-(chloromethyl)-3,5-dimethylbenzene in 50% yie...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Meng, Goldman, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272745/
https://www.ncbi.nlm.nih.gov/pubmed/26039335
http://dx.doi.org/10.3390/molecules200610122
_version_ 1783377228379193344
author Zhou, Meng
Goldman, Alan S.
author_facet Zhou, Meng
Goldman, Alan S.
author_sort Zhou, Meng
collection PubMed
description Pincer (Phebox)Ir(mesityl)(OAc) (2) (Phebox = 3,5-dimethylphenyl-2,6-bis(oxazolinyl)) complex, formed by benzylic C-H activation of mesitylene (1,3,5-trimethylbenzene) using (Phebox)Ir(OAc)(2)OH(2) (1), was treated with thionyl chloride to rapidly form 1-(chloromethyl)-3,5-dimethylbenzene in 50% yield at 23 °C. A green species was obtained at the end of reaction, which decomposed during flash column chromatography to form (Phebox)IrCl(2)OH(2) in 87% yield.
format Online
Article
Text
id pubmed-6272745
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62727452018-12-31 Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride Zhou, Meng Goldman, Alan S. Molecules Communication Pincer (Phebox)Ir(mesityl)(OAc) (2) (Phebox = 3,5-dimethylphenyl-2,6-bis(oxazolinyl)) complex, formed by benzylic C-H activation of mesitylene (1,3,5-trimethylbenzene) using (Phebox)Ir(OAc)(2)OH(2) (1), was treated with thionyl chloride to rapidly form 1-(chloromethyl)-3,5-dimethylbenzene in 50% yield at 23 °C. A green species was obtained at the end of reaction, which decomposed during flash column chromatography to form (Phebox)IrCl(2)OH(2) in 87% yield. MDPI 2015-06-01 /pmc/articles/PMC6272745/ /pubmed/26039335 http://dx.doi.org/10.3390/molecules200610122 Text en © 2015 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Zhou, Meng
Goldman, Alan S.
Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride
title Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride
title_full Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride
title_fullStr Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride
title_full_unstemmed Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride
title_short Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride
title_sort chlorination of (phebox)ir(mesityl)(oac) by thionyl chloride
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272745/
https://www.ncbi.nlm.nih.gov/pubmed/26039335
http://dx.doi.org/10.3390/molecules200610122
work_keys_str_mv AT zhoumeng chlorinationofpheboxirmesityloacbythionylchloride
AT goldmanalans chlorinationofpheboxirmesityloacbythionylchloride

Ejemplares similares