Cargando…

Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies

Copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC click chemistry, is an efficient method for bioconjugation aiming at chemical and biological applications. Herein, we demonstrate how the CuAAC method can provide novel phospholipid-protein conjugates with a high potential for the diagnostics...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maity, Arindam, Macaubas, Claudia, Mellins, Elizabeth, Astakhova, Kira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272759/ https://www.ncbi.nlm.nih.gov/pubmed/26046322 http://dx.doi.org/10.3390/molecules200610253

Ejemplares similares

Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases
por: Samuelsen, Simone V., et al.
Publicado: (2016)

Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens
por: Samuelsen, Simone, et al.
Publicado: (2018)

Epithelial MHC Class II Expression and Its Role in Antigen Presentation in the Gastrointestinal and Respiratory Tracts
por: Wosen, Jonathan E., et al.
Publicado: (2018)

Autoantibody Profiling in Lupus Patients using Synthetic Nucleic Acids
por: Klecka, Martin, et al.
Publicado: (2018)

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies
por: Samuelsen, Simone V., et al.
Publicado: (2016)

The MHC class II antigen presentation pathway in human monocytes differs by subset and is regulated by cytokines
por: Lee, Justin, et al.
Publicado: (2017)

The Other Function: Class II-Restricted Antigen Presentation by B Cells
por: Adler, Lital N., et al.
Publicado: (2017)

Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation
por: Wang, Nan, et al.
Publicado: (2015)

Enzyme-Free Detection of Mutations in Cancer DNA Using Synthetic Oligonucleotide Probes and Fluorescence Microscopy
por: Miotke, Laura, et al.
Publicado: (2015)

Developing an Antibody–Drug Conjugate Approach to Selective Inhibition of an Extracellular Protein
por: Love, Elizabeth A., et al.
Publicado: (2019)

Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies
por: Domljanovic, Ivana, et al.
Publicado: (2017)

Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies
por: Gliszczyńska, Anna, et al.
Publicado: (2017)

High Dimensional Analyses of Circulating Immune Cells in Psoriatic Arthritis Detects Elevated Phosphorylated STAT3
por: Macaubas, Claudia, et al.
Publicado: (2022)

Anti-phospholipid IgG antibodies detected by line immunoassay differentiate patients with anti-phospholipid syndrome and other autoimmune diseases
por: Nalli, Cecilia, et al.
Publicado: (2018)

Label-Free Colorimetric Detection of Influenza Antigen Based on an Antibody-Polydiacetylene Conjugate and Its Coated Polyvinylidene Difluoride Membrane
por: Jeong, Jae-pil, et al.
Publicado: (2017)

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110
por: Domínguez, Juan Manuel, et al.
Publicado: (2020)

Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation
por: Hamilton, Joseph Z., et al.
Publicado: (2021)

Phospholipid synthesis inside phospholipid membrane vesicles
por: Eto, Sumie, et al.
Publicado: (2022)

Rapid modification of antibodies on the surface of liposomes composed of high-affinity protein A-conjugated phospholipid for selective drug delivery
por: Hama, Susumu, et al.
Publicado: (2021)

A positive feedback loop reinforces the allergic immune response in human peanut allergy
por: Zhou, Xiaoying, et al.
Publicado: (2021)

Unmasking New Promises: Expanding the Antigen Landscape For Antibody–Drug Conjugates
por: Oberoi, Honey K., et al.
Publicado: (2021)

Impact of spontaneous liposome modification with phospholipid polymer-lipid conjugates on protein interactions
por: Suzuki, Haruna, et al.
Publicado: (2022)

Antibodies to synthetic citrullinated peptide epitope correlate with disease activity and flares in rheumatoid arthritis
por: Khatri, Sangita, et al.
Publicado: (2020)

Yeast display of MHC-II enables rapid identification of peptide ligands from protein antigens (RIPPA)
por: Liu, Rongzeng, et al.
Publicado: (2021)

The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2
por: Stremmel, Wolfgang, et al.
Publicado: (2019)

The Introduction of Pyrrolotetrathiafulvalene into Conjugated Architectures: Synthesis and Electronic Properties
por: Kanibolotsky, Alexander L, et al.
Publicado: (2008)

Synthesis of 5′-GalNAc-Conjugated Oligonucleotides: A Comparison of Solid and Solution-Phase Conjugation Strategies
por: Cedillo, Isaiah, et al.
Publicado: (2017)

Multicohort Analysis Identifies Monocyte Gene Signatures to Accurately Monitor Subset-Specific Changes in Human Diseases
por: Vallania, Francesco, et al.
Publicado: (2021)

Characterization of the Conjugation Pattern in Large Polysaccharide–Protein Conjugates by NMR Spectroscopy
por: Giuntini, Stefano, et al.
Publicado: (2017)

Cognitive Impairment in Anti-Phospholipid Syndrome and Anti-Phospholipid Antibody Carriers
por: Hassan, Fadi, et al.
Publicado: (2022)

Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes
por: Chen, Tao, et al.
Publicado: (2023)

Antiretinal antibody- proven autoimmune retinopathy
por: Abraham, Sharanya, et al.
Publicado: (2017)

Evaluation of Factors Influencing Antibody Reduction for Development of Antibody Drug Conjugates
por: Abdollahpour-Alitappeh, Meghdad, et al.
Publicado: (2017)

Synthesis and Biological Characterization of Monomeric and Tetrameric RGD‐Cryptophycin Conjugates
por: Borbély, Adina, et al.
Publicado: (2020)

New Senolysis Approach via Antibody–Drug Conjugate Targeting of the Senescent Cell Marker Apolipoprotein D for Skin Rejuvenation
por: Takaya, Kento, et al.
Publicado: (2023)

Interaction of poly(ethylene glycol)-conjugated phospholipids with supported lipid membranes and their influence on protein adsorption
por: Yamamoto, Toshihiro, et al.
Publicado: (2016)

Phospholipid-Conjugated PEG-b-PCL Copolymers as Precursors of Micellar Vehicles for Amphotericin B
por: Arias, Elsa R., et al.
Publicado: (2021)

Ethynylphosphonamidates for the Rapid and Cysteine‐Selective Generation of Efficacious Antibody–Drug Conjugates
por: Kasper, Marc‐André, et al.
Publicado: (2019)

Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy
por: Schwach, Jonathan, et al.
Publicado: (2020)

Urine Peptidomic and Targeted Plasma Protein Analyses in the Diagnosis and Monitoring of Systemic Juvenile Idiopathic Arthritis
por: Ling, Xuefeng B., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_sgigj36fmbb74bk9ga1d73f4a9