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Sevoflurane-Sulfobutylether-β-Cyclodextrin Complex: Preparation, Characterization, Cellular Toxicity, Molecular Modeling and Blood-Brain Barrier Transport Studies

The objective of the present investigation was to study the ability of sulfobutylether-β-cyclodextrin (SBEβCD) to form an inclusion complex with sevoflurane (SEV), a volatile anesthetic with poor water solubility. The inclusion complex was prepared, characterized and its cellular toxicity and blood-...

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Detalles Bibliográficos
Autores principales:	Shityakov, Sergey, Puskás, István, Pápai, Katalin, Salvador, Ellaine, Roewer, Norbert, Förster, Carola, Broscheit, Jens-Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272776/ https://www.ncbi.nlm.nih.gov/pubmed/26046323 http://dx.doi.org/10.3390/molecules200610264

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