Cargando…
Long-Term Stability of New Co-Amorphous Drug Binary Systems: Study of Glass Transitions as a Function of Composition and Shelf Time
The amorphous state is of particular interest in the pharmaceutical industry due to the higher solubility that amorphous active pharmaceutical ingredients show compared to their respective crystalline forms. Due to their thermodynamic instability, drugs in the amorphous state tend to recrystallize;...
Autores principales: | Martínez, Luz María, Videa, Marcelo, Sosa, Nahida González, Ramírez, José Héctor, Castro, Samuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272840/ https://www.ncbi.nlm.nih.gov/pubmed/27983640 http://dx.doi.org/10.3390/molecules21121712 |
Ejemplares similares
-
Co-Amorphous Simvastatin-Nifedipine with Enhanced Solubility for Possible Use in Combination Therapy of Hypertension and Hypercholesterolemia
por: Martínez-Jiménez, Cecilia, et al.
Publicado: (2018) -
The glass transition in high-density amorphous ice
por: Loerting, Thomas, et al.
Publicado: (2015) -
Measurements of growing surface tension of amorphous–amorphous interfaces on approaching the colloidal glass transition
por: Ganapathi, Divya, et al.
Publicado: (2018) -
Universal amorphous-amorphous transition in Ge(x)Se(100−x) glasses under pressure
por: Yildirim, Can, et al.
Publicado: (2016) -
On Structural Rearrangements Near the Glass Transition Temperature in Amorphous Silica
por: Ojovan, Michael I., et al.
Publicado: (2021)