Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc

Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1–7. Their structures and relative configuration were elucidated on the basis of extensive spectro...

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Autores principales: Li, Shi-Fei, Ding, Jia-Yin, Li, Ya-Ting, Hao, Xiao-Jiang, Li, Shun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272858/
https://www.ncbi.nlm.nih.gov/pubmed/27070557
http://dx.doi.org/10.3390/molecules21040457
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author Li, Shi-Fei
Ding, Jia-Yin
Li, Ya-Ting
Hao, Xiao-Jiang
Li, Shun-Lin
author_facet Li, Shi-Fei
Ding, Jia-Yin
Li, Ya-Ting
Hao, Xiao-Jiang
Li, Shun-Lin
author_sort Li, Shi-Fei
collection PubMed
description Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1–7. Their structures and relative configuration were elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR experiments. The antimicrobial activities of all isolated diterpenoids were evaluated against a panel of bacteria and fungi.
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spelling pubmed-62728582018-12-28 Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc Li, Shi-Fei Ding, Jia-Yin Li, Ya-Ting Hao, Xiao-Jiang Li, Shun-Lin Molecules Article Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1–7. Their structures and relative configuration were elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR experiments. The antimicrobial activities of all isolated diterpenoids were evaluated against a panel of bacteria and fungi. MDPI 2016-04-07 /pmc/articles/PMC6272858/ /pubmed/27070557 http://dx.doi.org/10.3390/molecules21040457 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Shi-Fei
Ding, Jia-Yin
Li, Ya-Ting
Hao, Xiao-Jiang
Li, Shun-Lin
Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
title Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
title_full Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
title_fullStr Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
title_full_unstemmed Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
title_short Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
title_sort antimicrobial diterpenoids of wedelia trilobata (l.) hitchc
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272858/
https://www.ncbi.nlm.nih.gov/pubmed/27070557
http://dx.doi.org/10.3390/molecules21040457
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