Cargando…

Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways

Capsaicin (CAP), a highly selective agonist for transient receptor potential vanilloid type 1 (TRPV1), has been widely reported to exhibit anti-oxidant, anti-inflammation and anticancer activities. Currently, several therapeutic approaches for bladder cancer (BCa) are available, but accompanied by u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Kaiyu, Wang, Gang, Cao, Rui, Liu, Tao, Qian, Guofeng, Guan, Xinyuan, Guo, Zhongqiang, Xiao, Yu, Wang, Xinghuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272872/ https://www.ncbi.nlm.nih.gov/pubmed/27775662 http://dx.doi.org/10.3390/molecules21101406

Ejemplares similares

Correction: Qian et al. Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways. Molecules 2016, 21, 1406
por: Qian, Kaiyu, et al.
Publicado: (2022)

Knockdown of SIRT1 Suppresses Bladder Cancer Cell Proliferation and Migration and Induces Cell Cycle Arrest and Antioxidant Response through FOXO3a-Mediated Pathways
por: Hu, Qingxuan, et al.
Publicado: (2017)

PPARγ inhibition regulates the cell cycle, proliferation and motility of bladder cancer cells
por: Cheng, Songtao, et al.
Publicado: (2019)

Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway
por: Wang, Gang, et al.
Publicado: (2016)

Silencing of HJURP induces dysregulation of cell cycle and ROS metabolism in bladder cancer cells via PPARγ-SIRT1 feedback loop
por: Cao, Rui, et al.
Publicado: (2017)

TRPM8 Inhibition Regulates the Proliferation, Migration and ROS Metabolism of Bladder Cancer Cells
por: Wang, Gang, et al.
Publicado: (2020)

Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells
por: Lin, Chia-Han, et al.
Publicado: (2013)

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway
por: Cao, Rui, et al.
Publicado: (2016)

PPARα gene is a diagnostic and prognostic biomarker in clear cell renal cell carcinoma by integrated bioinformatics analysis
por: Luo, Yongwen, et al.
Publicado: (2019)

The inhibitory effect of silencing CDCA3 on migration and proliferation in bladder urothelial carcinoma
por: Shen, Dexin, et al.
Publicado: (2021)

Pectolinarigenin inhibits bladder urothelial carcinoma cell proliferation by regulating DNA damage/autophagy pathways
por: Deng, Zhao, et al.
Publicado: (2023)

Co-expression network analysis identified six hub genes in association with progression and prognosis in human clear cell renal cell carcinoma (ccRCC)
por: Yuan, Lushun, et al.
Publicado: (2017)

A novel correlation between ATP5A1 gene expression and progression of human clear cell renal cell carcinoma identified by co-expression analysis
por: Yuan, Lushun, et al.
Publicado: (2018)

BORA regulates cell proliferation and migration in bladder cancer
por: Cheng, Songtao, et al.
Publicado: (2020)

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC
por: Wang, Yejinpeng, et al.
Publicado: (2023)

FOXO3a-ROS pathway is involved in androgen-induced proliferation of prostate cancer cell
por: Tao, Yan, et al.
Publicado: (2022)

Capsaicin Mediates Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells via Stabilizing and Activating p53
por: Jin, Junzhe, et al.
Publicado: (2014)

UBE2T silencing suppresses proliferation and induces cell cycle arrest and apoptosis in bladder cancer cells
por: Gong, Yan Qing, et al.
Publicado: (2016)

Identification of Biomarkers Associated With Pathological Stage and Prognosis of Clear Cell Renal Cell Carcinoma by Co-expression Network Analysis
por: Chen, Liang, et al.
Publicado: (2018)

Downregulation of SOX9 suppresses breast cancer cell proliferation and migration by regulating apoptosis and cell cycle arrest
por: Wang, Yu-Feng, et al.
Publicado: (2021)

Epigenetic signature predicts overall survival clear cell renal cell carcinoma
por: Wang, Yejinpeng, et al.
Publicado: (2020)

Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation
por: Wang, Xinhong, et al.
Publicado: (2016)

Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway
por: Tang, Yan-Lai, et al.
Publicado: (2016)

Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis
por: Yuan, Lushun, et al.
Publicado: (2017)

Effect of TRPV2 cation channels on the proliferation, migration and invasion of 5637 bladder cancer cells
por: LIU, QUANLIANG, et al.
Publicado: (2013)

The role and function of PPARγ in bladder cancer
por: Peng, Tianchen, et al.
Publicado: (2020)

The immune‐related biomarker TEK inhibits the development of clear cell renal cell carcinoma (ccRCC) by regulating AKT phosphorylation
por: Chen, Siming, et al.
Publicado: (2021)

Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells
por: Hong, Su Hyun, et al.
Publicado: (2019)

Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
por: Zhang, Renjie, et al.
Publicado: (2020)

Ginsenoside Rg3 suppresses the proliferation of prostate cancer cell line PC3 through ROS-induced cell cycle arrest
por: Peng, Yanfei, et al.
Publicado: (2019)

Bioinformatics and functional analyses of key genes and pathways in human clear cell renal cell carcinoma
por: Wang, Jinxing, et al.
Publicado: (2018)

Immune‐related signature predicts the prognosis and immunotherapy benefit in bladder cancer
por: Wang, Yejinpeng, et al.
Publicado: (2020)

Trifluoperazine Inhibits Mesangial Cell Proliferation by Arresting Cell Cycle-Dependent Mechanisms
por: Wang, Baodong, et al.
Publicado: (2017)

Xanthohumol Induces ROS through NADPH Oxidase, Causes Cell Cycle Arrest and Apoptosis
por: Wang, Chun-Ming, et al.
Publicado: (2021)

African Swine Fever Virus Structural Protein p17 Inhibits Cell Proliferation through ER Stress—ROS Mediated Cell Cycle Arrest
por: Xia, Nengwen, et al.
Publicado: (2020)

ACAT1 and Metabolism-Related Pathways Are Essential for the Progression of Clear Cell Renal Cell Carcinoma (ccRCC), as Determined by Co-expression Network Analysis
por: Chen, Liang, et al.
Publicado: (2019)

Identification of 9 key genes and small molecule drugs in clear cell renal cell carcinoma
por: Luo, Yongwen, et al.
Publicado: (2019)

Novel Biomarkers Associated With Progression and Prognosis of Bladder Cancer Identified by Co-expression Analysis
por: Wang, Yejinpeng, et al.
Publicado: (2019)

Roles of ROS and cell cycle arrest in the genotoxicity induced by gold nanorod core/silver shell nanostructure
por: Wang, Dan, et al.
Publicado: (2020)

Identification and bioinformatics analysis of miRNAs associated with human muscle invasive bladder cancer
por: Chen, Liang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rm51n44lcisgbq5s17k2pjcsgt