Cargando…
20(S)-Protopanaxadiol Phospholipid Complex: Process Optimization, Characterization, In Vitro Dissolution and Molecular Docking Studies
20(S)-Protopanaxadiol (PPD), a bioactive compound extracted from ginseng, possesses cardioprotective, neuroprotective, anti-inflammatory, antiestrogenic, anticancer and anxiolytic effects. However, the clinical application of PPD is limited by its weak aqueous solubility. In this study, we optimized...
Autores principales: | Pu, Yiqiong, Zhang, Xitong, Zhang, Qi, Wang, Bing, Chen, Yuxi, Zang, Chuanqi, Wang, Yuqin, Dong, Tina Ting-Xia, Zhang, Tong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272886/ https://www.ncbi.nlm.nih.gov/pubmed/27775578 http://dx.doi.org/10.3390/molecules21101396 |
Ejemplares similares
-
Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol
por: Zhang, Qi, et al.
Publicado: (2017) -
Development of 20(S)-Protopanaxadiol-Loaded SNEDDS Preconcentrate Using Comprehensive Phase Diagram for the Enhanced Dissolution and Oral Bioavailability
por: Kim, Young Hoon, et al.
Publicado: (2020) -
Computational and experimental characterization of estrogenic activities of 20(S, R)-protopanaxadiol and 20(S, R)-protopanaxatriol
por: Zhang, Tiehua, et al.
Publicado: (2020) -
Molecular Insight into Stereoselective ADME Characteristics of C20-24 Epimeric Epoxides of Protopanaxadiol by Docking Analysis
por: Guo, Wenna, et al.
Publicado: (2020) -
Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways
por: GAO, JIAN-LI, et al.
Publicado: (2013)