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Nanopore Event-Transduction Signal Stabilization for Wide pH Range under Extreme Chaotrope Conditions
Operation of an α-hemolysin nanopore transduction detector is found to be surprisingly robust over a critical range of pH (6–9), including physiological pH = 7.4 and polymerase chain reaction (PCR) pH = 8.4, and extreme chaotrope concentration, including 5 M urea. The engineered transducer molecule...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272909/ https://www.ncbi.nlm.nih.gov/pubmed/26985886 http://dx.doi.org/10.3390/molecules21030346 |