Chemo-Enzymatic Synthesis of Chiral Epoxides Ethyl and Methyl (S)-3-(Oxiran-2-yl)propanoates from Renewable Levoglucosenone: An Access to Enantiopure (S)-Dairy Lactone

Chiral epoxides—such as ethyl and methyl (S)-3-(oxiran-2-yl)propanoates ((S)-1a/1b)—are valuable precursors in many chemical syntheses. Until recently, these compounds were synthesized from glutamic acid in four steps (deamination, reduction, tosylation and epoxide formation) in low to moderate over...

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Detalles Bibliográficos
Autores principales: Peru, Aurélien A. M., Flourat, Amandine L., Gunawan, Christian, Raverty, Warwick, Jevric, Martyn, Greatrex, Ben W., Allais, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272917/
https://www.ncbi.nlm.nih.gov/pubmed/27483225
http://dx.doi.org/10.3390/molecules21080988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272917/
https://www.ncbi.nlm.nih.gov/pubmed/27483225
http://dx.doi.org/10.3390/molecules21080988

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