Cargando…
Capsaicin Inhibits Multiple Bladder Cancer Cell Phenotypes by Inhibiting Tumor-Associated NADH Oxidase (tNOX) and Sirtuin1 (SIRT1)
Bladder cancer is one of the most frequent cancers among males, and its poor survival rate reflects problems with aggressiveness and chemo-resistance. Recent interest has focused on the use of chemopreventatives (nontoxic natural agents that may suppress cancer progression) to induce targeted apopto...
Autores principales: | Lin, Ming-Hung, Lee, Yi-Hui, Cheng, Hsiao-Ling, Chen, Huei-Yu, Jhuang, Fong-Han, Chueh, Pin Ju |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272932/ https://www.ncbi.nlm.nih.gov/pubmed/27367652 http://dx.doi.org/10.3390/molecules21070849 |
Ejemplares similares
-
Tumor-associated NADH oxidase (tNOX)-NAD(+)-sirtuin 1 axis contributes to oxaliplatin-induced apoptosis of gastric cancer cells
por: Chen, Huei-Yu, et al.
Publicado: (2017) -
Capsaicin Inhibited Aggressive Phenotypes through Downregulation of Tumor-Associated NADH Oxidase (tNOX) by POU Domain Transcription Factor POU3F2
por: Chen, Hung Yen, et al.
Publicado: (2016) -
Capsaicin Targets tNOX (ENOX2) to Inhibit G1 Cyclin/CDK Complex, as Assessed by the Cellular Thermal Shift Assay (CETSA)
por: Islam, Atikul, et al.
Publicado: (2019) -
Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-b]furan-5,10-diones in Hepatocellular Carcinoma Cells
por: Lin, Chia-Yang, et al.
Publicado: (2019) -
Benzo[b]thiophenesulphonamide 1,1-dioxide derivatives inhibit tNOX activity in a redox state-dependent manner
por: Encío, I, et al.
Publicado: (2005)