Chemical Constituents of Phaius mishmensis

The partitioned n-hexane, CHCl(3), and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1)...

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Detalles Bibliográficos
Autores principales: Jao, Chen-Wei, Hung, Tzu-Heng, Chang, Chi-Fen, Chuang, Ta-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272941/
https://www.ncbi.nlm.nih.gov/pubmed/27886100
http://dx.doi.org/10.3390/molecules21111605
Descripción
Sumario:The partitioned n-hexane, CHCl(3), and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7′R,8′R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods.

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