Chemical Constituents of Phaius mishmensis

The partitioned n-hexane, CHCl(3), and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1)...

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Autores principales: Jao, Chen-Wei, Hung, Tzu-Heng, Chang, Chi-Fen, Chuang, Ta-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272941/
https://www.ncbi.nlm.nih.gov/pubmed/27886100
http://dx.doi.org/10.3390/molecules21111605
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author Jao, Chen-Wei
Hung, Tzu-Heng
Chang, Chi-Fen
Chuang, Ta-Hsien
author_facet Jao, Chen-Wei
Hung, Tzu-Heng
Chang, Chi-Fen
Chuang, Ta-Hsien
author_sort Jao, Chen-Wei
collection PubMed
description The partitioned n-hexane, CHCl(3), and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7′R,8′R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods.
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spelling pubmed-62729412018-12-28 Chemical Constituents of Phaius mishmensis Jao, Chen-Wei Hung, Tzu-Heng Chang, Chi-Fen Chuang, Ta-Hsien Molecules Article The partitioned n-hexane, CHCl(3), and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7′R,8′R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods. MDPI 2016-11-23 /pmc/articles/PMC6272941/ /pubmed/27886100 http://dx.doi.org/10.3390/molecules21111605 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jao, Chen-Wei
Hung, Tzu-Heng
Chang, Chi-Fen
Chuang, Ta-Hsien
Chemical Constituents of Phaius mishmensis
title Chemical Constituents of Phaius mishmensis
title_full Chemical Constituents of Phaius mishmensis
title_fullStr Chemical Constituents of Phaius mishmensis
title_full_unstemmed Chemical Constituents of Phaius mishmensis
title_short Chemical Constituents of Phaius mishmensis
title_sort chemical constituents of phaius mishmensis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272941/
https://www.ncbi.nlm.nih.gov/pubmed/27886100
http://dx.doi.org/10.3390/molecules21111605
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