Five New Biphenanthrenes from Cremastra appendiculata

Five new biphenanthrenes, cremaphenanthrenes A–E (1–5), along with six known ones, were isolated from the ethanolic extract of the tubers of Cremastra appendiculata (D. Don) Makino (Orchidaceae). Their structures were elucidated on the basis of extensive spectroscopic analyses. All the compounds obt...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Liang, Li, Jun, Zeng, Ke-Wu, Jiang, Yong, Tu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272948/
https://www.ncbi.nlm.nih.gov/pubmed/27548132
http://dx.doi.org/10.3390/molecules21081089
_version_ 1783377271337254912
author Liu, Liang
Li, Jun
Zeng, Ke-Wu
Jiang, Yong
Tu, Peng-Fei
author_facet Liu, Liang
Li, Jun
Zeng, Ke-Wu
Jiang, Yong
Tu, Peng-Fei
author_sort Liu, Liang
collection PubMed
description Five new biphenanthrenes, cremaphenanthrenes A–E (1–5), along with six known ones, were isolated from the ethanolic extract of the tubers of Cremastra appendiculata (D. Don) Makino (Orchidaceae). Their structures were elucidated on the basis of extensive spectroscopic analyses. All the compounds obtained were tested in vitro for cytotoxic activities against colon (HCT-116), cervix (Hela), and breast (MDA-MB-231) cancer cell lines. They all showed moderate or weak cytotoxicities to the above cancer cell lines.
format Online
Article
Text
id pubmed-6272948
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62729482018-12-28 Five New Biphenanthrenes from Cremastra appendiculata Liu, Liang Li, Jun Zeng, Ke-Wu Jiang, Yong Tu, Peng-Fei Molecules Article Five new biphenanthrenes, cremaphenanthrenes A–E (1–5), along with six known ones, were isolated from the ethanolic extract of the tubers of Cremastra appendiculata (D. Don) Makino (Orchidaceae). Their structures were elucidated on the basis of extensive spectroscopic analyses. All the compounds obtained were tested in vitro for cytotoxic activities against colon (HCT-116), cervix (Hela), and breast (MDA-MB-231) cancer cell lines. They all showed moderate or weak cytotoxicities to the above cancer cell lines. MDPI 2016-08-19 /pmc/articles/PMC6272948/ /pubmed/27548132 http://dx.doi.org/10.3390/molecules21081089 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Liang
Li, Jun
Zeng, Ke-Wu
Jiang, Yong
Tu, Peng-Fei
Five New Biphenanthrenes from Cremastra appendiculata
title Five New Biphenanthrenes from Cremastra appendiculata
title_full Five New Biphenanthrenes from Cremastra appendiculata
title_fullStr Five New Biphenanthrenes from Cremastra appendiculata
title_full_unstemmed Five New Biphenanthrenes from Cremastra appendiculata
title_short Five New Biphenanthrenes from Cremastra appendiculata
title_sort five new biphenanthrenes from cremastra appendiculata
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272948/
https://www.ncbi.nlm.nih.gov/pubmed/27548132
http://dx.doi.org/10.3390/molecules21081089
work_keys_str_mv AT liuliang fivenewbiphenanthrenesfromcremastraappendiculata
AT lijun fivenewbiphenanthrenesfromcremastraappendiculata
AT zengkewu fivenewbiphenanthrenesfromcremastraappendiculata
AT jiangyong fivenewbiphenanthrenesfromcremastraappendiculata
AT tupengfei fivenewbiphenanthrenesfromcremastraappendiculata

Ejemplares similares