An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin

Scutellarein (2), which is an important in vivo metabolite of scutellarin (1), was synthesized from 3,4,5-trimethoxyphenol (3) in high yield in four steps. This strategy relies on acetylation, aldolization, cyclization and hydrolysis reactions, respectively.

Detalles Bibliográficos
Autores principales: Dong, Ze-Xi, Li, Nian-Guang, Zhang, Peng-Xuan, Gu, Ting, Wu, Wen-Yu, Shi, Zhi-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272953/
https://www.ncbi.nlm.nih.gov/pubmed/26927039
http://dx.doi.org/10.3390/molecules21030263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272953/
https://www.ncbi.nlm.nih.gov/pubmed/26927039
http://dx.doi.org/10.3390/molecules21030263

Ejemplares similares