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An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin
Scutellarein (2), which is an important in vivo metabolite of scutellarin (1), was synthesized from 3,4,5-trimethoxyphenol (3) in high yield in four steps. This strategy relies on acetylation, aldolization, cyclization and hydrolysis reactions, respectively.
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272953/ https://www.ncbi.nlm.nih.gov/pubmed/26927039 http://dx.doi.org/10.3390/molecules21030263 |