Cargando…
Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties
We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission trans...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272985/ https://www.ncbi.nlm.nih.gov/pubmed/27314316 http://dx.doi.org/10.3390/molecules21060774 |
_version_ | 1783377280036241408 |
---|---|
author | Chiguvare, Herbert Oyedeji, Opeoluwa O. Matewu, Reuben Aremu, Olukayode Oyemitan, Idris A. Oyedeji, Adebola O. Nkeh-Chungag, Benedicta N. Songca, Sandile P. Mohan, Sneha Oluwafemi, Oluwatobi S. |
author_facet | Chiguvare, Herbert Oyedeji, Opeoluwa O. Matewu, Reuben Aremu, Olukayode Oyemitan, Idris A. Oyedeji, Adebola O. Nkeh-Chungag, Benedicta N. Songca, Sandile P. Mohan, Sneha Oluwafemi, Oluwatobi S. |
author_sort | Chiguvare, Herbert |
collection | PubMed |
description | We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission transform microscopy (TEM) to confirm the formation of silver nanoparticles. Phytochemical screening of the ethanolic extract revealed the presence of glycosides, proteins, tannins, alkaloids, flavonoids and saponins. The absorption spectra showed that the synthesis is temperature and time dependent. The TEM analysis showed that the as-synthesised Ag-NPs are polydispersed and spherical in shape with average particle diameter of 19.95 ± 7.76 nm while the FTIR results confirmed the reduction and capping of the as-synthesised Ag-NPs by the phytochemicals present in the ethanolic extract. The analgesic study indicated that the combined effect of the plant extract and Ag-NPs is more effective in pain management than both the aspirin drug and the extract alone. |
format | Online Article Text |
id | pubmed-6272985 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62729852018-12-28 Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties Chiguvare, Herbert Oyedeji, Opeoluwa O. Matewu, Reuben Aremu, Olukayode Oyemitan, Idris A. Oyedeji, Adebola O. Nkeh-Chungag, Benedicta N. Songca, Sandile P. Mohan, Sneha Oluwafemi, Oluwatobi S. Molecules Article We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission transform microscopy (TEM) to confirm the formation of silver nanoparticles. Phytochemical screening of the ethanolic extract revealed the presence of glycosides, proteins, tannins, alkaloids, flavonoids and saponins. The absorption spectra showed that the synthesis is temperature and time dependent. The TEM analysis showed that the as-synthesised Ag-NPs are polydispersed and spherical in shape with average particle diameter of 19.95 ± 7.76 nm while the FTIR results confirmed the reduction and capping of the as-synthesised Ag-NPs by the phytochemicals present in the ethanolic extract. The analgesic study indicated that the combined effect of the plant extract and Ag-NPs is more effective in pain management than both the aspirin drug and the extract alone. MDPI 2016-06-14 /pmc/articles/PMC6272985/ /pubmed/27314316 http://dx.doi.org/10.3390/molecules21060774 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chiguvare, Herbert Oyedeji, Opeoluwa O. Matewu, Reuben Aremu, Olukayode Oyemitan, Idris A. Oyedeji, Adebola O. Nkeh-Chungag, Benedicta N. Songca, Sandile P. Mohan, Sneha Oluwafemi, Oluwatobi S. Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
title | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
title_full | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
title_fullStr | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
title_full_unstemmed | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
title_short | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
title_sort | synthesis of silver nanoparticles using buchu plant extracts and their analgesic properties |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272985/ https://www.ncbi.nlm.nih.gov/pubmed/27314316 http://dx.doi.org/10.3390/molecules21060774 |
work_keys_str_mv | AT chiguvareherbert synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT oyedejiopeoluwao synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT matewureuben synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT aremuolukayode synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT oyemitanidrisa synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT oyedejiadebolao synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT nkehchungagbenedictan synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT songcasandilep synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT mohansneha synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties AT oluwafemioluwatobis synthesisofsilvernanoparticlesusingbuchuplantextractsandtheiranalgesicproperties |