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Synthesis and Cytotoxic Effect of Some Novel 1,2-Dihydropyridin-3-carbonitrile and Nicotinonitrile Derivatives

1-(2,4-Dichlorophenyl)-3-(4-fluorophenyl)propen-1-one (1) was prepared and reacted with an active methylene compound (ethyl cyanoacetate) in the presence of ammonium acetate to give the corresponding cyanopyridone 2. Compound 2 reacted with hydrazine hydrate, malononitrile, ethyl bromoacetate and ph...

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Detalles Bibliográficos
Autores principales:	M. Flefel, Eman, S. Abbas, Hebat-Allah, E. Abdel Mageid, Randa, A. Zaghary, Wafaa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272992/ https://www.ncbi.nlm.nih.gov/pubmed/26729087 http://dx.doi.org/10.3390/molecules21010030

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