Gold Nanocluster Decorated Polypeptide/DNA Complexes for NIR Light and Redox Dual-Responsive Gene Transfection

Endo/lysosomal escape and subsequent nuclear translocation are recognized as the two major challenges for efficient gene transfection. Herein, nuclear localization signal (NLS) peptide sequences and oligomeric lysine sequences were crosslinked via disulfide bonds to obtain glutathione (GSH) reducibl...

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Detalles Bibliográficos
Autores principales: Lei, Qi, Hu, Jing-Jing, Rong, Lei, Cheng, Han, Sun, Yun-Xia, Zhang, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273015/
https://www.ncbi.nlm.nih.gov/pubmed/27556436
http://dx.doi.org/10.3390/molecules21081103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273015/
https://www.ncbi.nlm.nih.gov/pubmed/27556436
http://dx.doi.org/10.3390/molecules21081103

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