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Gold Nanocluster Decorated Polypeptide/DNA Complexes for NIR Light and Redox Dual-Responsive Gene Transfection
Endo/lysosomal escape and subsequent nuclear translocation are recognized as the two major challenges for efficient gene transfection. Herein, nuclear localization signal (NLS) peptide sequences and oligomeric lysine sequences were crosslinked via disulfide bonds to obtain glutathione (GSH) reducibl...
Autores principales: | Lei, Qi, Hu, Jing-Jing, Rong, Lei, Cheng, Han, Sun, Yun-Xia, Zhang, Xian-Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273015/ https://www.ncbi.nlm.nih.gov/pubmed/27556436 http://dx.doi.org/10.3390/molecules21081103 |
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