Cargando…

A Novel Synthesis of Fused Uracils: Indenopyrimidopyridazines, Pyrimidopyridazines, and Pyrazolopyrimidines for Antimicrobial and Antitumor Evalution

A variety of different compounds of fused uracils were prepared simply by the heating of 6-hydrazinyl-1-methyl-, 6-hydrazinyl-1-propyl-, or 6-hydrazinyl-1,3-dipropyluracil under reflux with ninhydrin, isatin, benzylidene malononitrile, benzylylidene ethyl cyanoacetate, benzil, and phenacyl bromide d...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Kalyoubi, Samar, Agili, Fatimah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273033/ https://www.ncbi.nlm.nih.gov/pubmed/27983644 http://dx.doi.org/10.3390/molecules21121714

Ejemplares similares

Synthesis, In Silico Prediction and In Vitro Evaluation of Antimicrobial Activity, DFT Calculation and Theoretical Investigation of Novel Xanthines and Uracil Containing Imidazolone Derivatives
por: El-Kalyoubi, Samar, et al.
Publicado: (2021)

Synthesis, In Silico Prediction and In Vitro Evaluation of Antitumor Activities of Novel Pyrido[2,3-d]pyrimidine, Xanthine and Lumazine Derivatives
por: El-Kalyoubi, Samar, et al.
Publicado: (2020)

One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines
por: El-Kalyoubi, Samar A., et al.
Publicado: (2017)

Erratum to: One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines
por: El-Kalyoubi, Samar A., et al.
Publicado: (2017)

Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity †
por: El-kalyoubi, Samar, et al.
Publicado: (2015)

Design, Synthesis and Antitumor Evaluation of Novel Pyrazolopyrimidines and Pyrazoloquinazolines
por: El-Naggar, Mohamed, et al.
Publicado: (2018)

Correction: El-kalyoubi, S.; et al. Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity. Molecules, 2015, 20, 19263--19276
por: El-kalyoubi, Samar, et al.
Publicado: (2018)

Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors
por: Elbatrawy, Omnia R., et al.
Publicado: (2023)

Synthesis and Antimicrobial Evaluation of Novel Pyrazolopyrimidines Incorporated with Mono- and Diphenylsulfonyl Groups
por: Alsaedi, Amani M. R., et al.
Publicado: (2019)

Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling
por: El-Kalyoubi, Samar, et al.
Publicado: (2023)

Synthesis and Isomerization of Some Novel Pyrazolopyrimidine and Pyrazolotriazolopyrimidine Derivatives
por: Rashad, Aymn E., et al.
Publicado: (2014)

Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors
por: El-Kalyoubi, Samar A., et al.
Publicado: (2022)

Trisubstituted Pyrazolopyrimidines as Novel Angiogenesis Inhibitors
por: Weitensteiner, Sabine B., et al.
Publicado: (2013)

Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAF(V600E)
por: El-Kalyoubi, Samar A., et al.
Publicado: (2023)

Reliable Functionalization of 5,6‐Fused Bicyclic N‐Heterocycles Pyrazolopyrimidines and Imidazopyridazines via Zinc and Magnesium Organometallics
por: Kumar Rout, Saroj, et al.
Publicado: (2022)

Novel functionalized monomers based on kojic acid: snythesis, characterization, polymerization and evalution of antimicrobial activity
por: Saraei, Mahnaz, et al.
Publicado: (2016)

Synthesis and Biological Evaluation of N- Pyrazolyl Derivatives and Pyrazolopyrimidine Bearing a Biologically Active Sulfonamide Moiety as Potential Antimicrobial Agent
por: Hafez, Hend N., et al.
Publicado: (2016)

Review of Progress in Quantitative Nondestructive Evalutation
por: Thompson, Donald O, et al.
Publicado: (2007)

The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines
por: C. S. Pinheiro, Luiz, et al.
Publicado: (2019)

Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent
por: El-Kalyoubi, Samar A.
Publicado: (2018)

Synthesis and Antimicrobial Activity of Some Novel 5-Alkyl-6-Substituted Uracils and Related Derivatives
por: Al-Turkistani, Abdulghafoor A., et al.
Publicado: (2011)

Synthesis, Structural Elucidation, and In Vitro Antitumor Activities of Some Pyrazolopyrimidines and Schiff Bases Derived from 5-Amino-3-(arylamino)-1H-pyrazole-4-carboxamides
por: Hafez, Taghrid S., et al.
Publicado: (2013)

One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein
por: El-Kalyoubi, Samar A., et al.
Publicado: (2022)

Pyrazolopyrimidines: Potent Inhibitors Targeting the Capsid of Rhino- and Enteroviruses
por: Makarov, Vadim A, et al.
Publicado: (2015)

Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis
por: McGillan, Paul, et al.
Publicado: (2021)

Evalutation of hand hygiene compliance in medical educational videos
por: Longtin, Y, et al.
Publicado: (2011)

An evalution of compressive strength of newer nanocomposite: An in vitro study
por: Hegde, Mithra N, et al.
Publicado: (2011)

$\pi_[-}$-mass and vacuum polarization - a re-evalution.
por: Backenstoss, Gerhard, et al.
Publicado: (1973)

Evalution of the “Iceberg Phenomenon” in Johne's Disease through Mathematical Modelling
por: Magombedze, Gesgam, et al.
Publicado: (2013)

Chronically Discharging Ears: Evalution with High Resolution Computed Tomography
por: Bhalla, Ashu Seith, et al.
Publicado: (2017)

Synthesis, In Silico and In Vitro Characterization of Novel N,N-Substituted Pyrazolopyrimidine Acetamide Derivatives for the 18KDa Translocator Protein (TSPO)
por: Park, Jaekyung, et al.
Publicado: (2023)

N–N Bond-Forming Cyclization for the One-Pot Synthesis of N-Aryl[3,4-d]pyrazolopyrimidines
por: Evans, Lindsay E., et al.
Publicado: (2012)

EVALUTION OF UNILATERAL ELECTRO-CONVULSIVE THERAPY (A double blind study)
por: Chatterjee, S. B., et al.
Publicado: (1980)

SHILAJIT: EVALUTION OF ITS EFFECTS ON BLOOD CHEMISTRY OF NORMAL HUMAN SUBJECTS
por: Sharma, Praveen, et al.
Publicado: (2003)

Evalution of In Vitro Effect of Flavonoids on Human Low-Density Lipoprotein Carbamylation
por: Ghaffari, Mohammad Ali, et al.
Publicado: (2010)

Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents
por: Abd El-Hameed, Rania Helmy, et al.
Publicado: (2021)

Evalution of anti-ulcer activity of Polyalthia longifolia (Sonn.) Thwaites in experimental animals
por: Malairajan, P., et al.
Publicado: (2008)

Ringberg Symposium of Science Between Evalutation and Innovation : a conference on peer review
por: Osborn, Mary
Publicado: (2003)

Evalutation of the perceived quality in the Orthopedics/Traumatology Unit at Carlo Poma Hospital in Mantova
por: Daniela, Pasquali, et al.
Publicado: (2019)

Zinc Oxide Nanoparticles and Synthesized Pyrazolopyrimidine Alleviate Diabetic Effects in Rats Induced by Type II Diabetes
por: Gadoa, Zahraa Alaaeldein, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f893f8gc0sk8msnqpcjge8tf19