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Synthesis of Hydroxymethylenebisphosphonic Acid Derivatives in Different Solvents
The syntheses of hydroxymethylenebisphosphonic acid derivatives (dronic acid derivatives) starting from the corresponding substituted acetic acids and P-reagents, mainly phosphorus trichloride and phosphorous acid are surveyed according to the solvents applied. The nature of the solvent is a critica...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273038/ https://www.ncbi.nlm.nih.gov/pubmed/27529200 http://dx.doi.org/10.3390/molecules21081046 |