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Optimization and Biodistribution of [(11)C]-TKF, An Analog of Tau Protein Imaging Agent [(18)F]-THK523

The quantification of neurofibrillary tangles (NFTs) using specific PET tracers can facilitate the diagnosis of Alzheimer’s disease (AD) and allow monitoring of disease progression and treatment efficacy. [(18)F]-THK523 has shown high affinity and selectivity for tau pathology. However, its high ret...

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Detalles Bibliográficos
Autores principales:	Kong, Yanyan, Guan, Yihui, Hua, Fengchun, Zhang, Zhengwei, Lu, Xiuhong, Zhu, Tengfang, Zhao, Bizeng, Zhu, Jianhua, Li, Cong, Chen, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273120/ https://www.ncbi.nlm.nih.gov/pubmed/27527142 http://dx.doi.org/10.3390/molecules21081019

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