Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola

Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived fungus Corynespora cassiicola XS-20090I7. Their st...

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Autores principales: Zhao, Dong-Lin, Shao, Chang-Lun, Wang, Chao-Yi, Wang, Mei, Yang, Lu-Jia, Wang, Chang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273126/
https://www.ncbi.nlm.nih.gov/pubmed/26828473
http://dx.doi.org/10.3390/molecules21020160
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author Zhao, Dong-Lin
Shao, Chang-Lun
Wang, Chao-Yi
Wang, Mei
Yang, Lu-Jia
Wang, Chang-Yun
author_facet Zhao, Dong-Lin
Shao, Chang-Lun
Wang, Chao-Yi
Wang, Mei
Yang, Lu-Jia
Wang, Chang-Yun
author_sort Zhao, Dong-Lin
collection PubMed
description Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived fungus Corynespora cassiicola XS-20090I7. Their structures including absolute configurations were determined by spectroscopic data and electronic circular dichroism (ECD) spectra. Compounds 4 and 5 showed cytotoxicity against human promyelocytic leukemia HL-60 and human cervical carcinoma HeLa cell lines.
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spelling pubmed-62731262018-12-28 Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola Zhao, Dong-Lin Shao, Chang-Lun Wang, Chao-Yi Wang, Mei Yang, Lu-Jia Wang, Chang-Yun Molecules Article Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived fungus Corynespora cassiicola XS-20090I7. Their structures including absolute configurations were determined by spectroscopic data and electronic circular dichroism (ECD) spectra. Compounds 4 and 5 showed cytotoxicity against human promyelocytic leukemia HL-60 and human cervical carcinoma HeLa cell lines. MDPI 2016-01-28 /pmc/articles/PMC6273126/ /pubmed/26828473 http://dx.doi.org/10.3390/molecules21020160 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhao, Dong-Lin
Shao, Chang-Lun
Wang, Chao-Yi
Wang, Mei
Yang, Lu-Jia
Wang, Chang-Yun
Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
title Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
title_full Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
title_fullStr Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
title_full_unstemmed Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
title_short Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola
title_sort naphthalenones and depsidones from a sponge-derived strain of the fungus corynespora cassiicola
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273126/
https://www.ncbi.nlm.nih.gov/pubmed/26828473
http://dx.doi.org/10.3390/molecules21020160
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