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Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules
Cellulose acetate (CA) nanoparticles were combined with two antimicrobial agents, namely lemongrass (LG) essential oil and Cu-ferrite nanoparticles. The preparation method of CA nanocapsules (NCs), with the two antimicrobial agents, was based on the nanoprecipitation method using the solvent/anti-so...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273162/ https://www.ncbi.nlm.nih.gov/pubmed/27104514 http://dx.doi.org/10.3390/molecules21040520 |
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author | Liakos, Ioannis L. Abdellatif, Mohamed H. Innocenti, Claudia Scarpellini, Alice Carzino, Riccardo Brunetti, Virgilio Marras, Sergio Brescia, Rosaria Drago, Filippo Pompa, Pier Paolo |
author_facet | Liakos, Ioannis L. Abdellatif, Mohamed H. Innocenti, Claudia Scarpellini, Alice Carzino, Riccardo Brunetti, Virgilio Marras, Sergio Brescia, Rosaria Drago, Filippo Pompa, Pier Paolo |
author_sort | Liakos, Ioannis L. |
collection | PubMed |
description | Cellulose acetate (CA) nanoparticles were combined with two antimicrobial agents, namely lemongrass (LG) essential oil and Cu-ferrite nanoparticles. The preparation method of CA nanocapsules (NCs), with the two antimicrobial agents, was based on the nanoprecipitation method using the solvent/anti-solvent technique. Several physical and chemical analyses were performed to characterize the resulting NCs and to study their formation mechanism. The size of the combined antimicrobial NCs was found to be ca. 220 nm. The presence of Cu-ferrites enhanced the attachment of LG essential oil into the CA matrix. The magnetic properties of the combined construct were weak, due to the shielding of Cu-ferrites from the polymeric matrix, making them available for drug delivery applications where spontaneous magnetization effects should be avoided. The antimicrobial properties of the NCs were significantly enhanced with respect to CA/LG only. This work opens novel routes for the development of organic/inorganic nanoparticles with exceptional antimicrobial activities. |
format | Online Article Text |
id | pubmed-6273162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62731622018-12-28 Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules Liakos, Ioannis L. Abdellatif, Mohamed H. Innocenti, Claudia Scarpellini, Alice Carzino, Riccardo Brunetti, Virgilio Marras, Sergio Brescia, Rosaria Drago, Filippo Pompa, Pier Paolo Molecules Article Cellulose acetate (CA) nanoparticles were combined with two antimicrobial agents, namely lemongrass (LG) essential oil and Cu-ferrite nanoparticles. The preparation method of CA nanocapsules (NCs), with the two antimicrobial agents, was based on the nanoprecipitation method using the solvent/anti-solvent technique. Several physical and chemical analyses were performed to characterize the resulting NCs and to study their formation mechanism. The size of the combined antimicrobial NCs was found to be ca. 220 nm. The presence of Cu-ferrites enhanced the attachment of LG essential oil into the CA matrix. The magnetic properties of the combined construct were weak, due to the shielding of Cu-ferrites from the polymeric matrix, making them available for drug delivery applications where spontaneous magnetization effects should be avoided. The antimicrobial properties of the NCs were significantly enhanced with respect to CA/LG only. This work opens novel routes for the development of organic/inorganic nanoparticles with exceptional antimicrobial activities. MDPI 2016-04-20 /pmc/articles/PMC6273162/ /pubmed/27104514 http://dx.doi.org/10.3390/molecules21040520 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Liakos, Ioannis L. Abdellatif, Mohamed H. Innocenti, Claudia Scarpellini, Alice Carzino, Riccardo Brunetti, Virgilio Marras, Sergio Brescia, Rosaria Drago, Filippo Pompa, Pier Paolo Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules |
title | Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules |
title_full | Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules |
title_fullStr | Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules |
title_full_unstemmed | Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules |
title_short | Antimicrobial Lemongrass Essential Oil—Copper Ferrite Cellulose Acetate Nanocapsules |
title_sort | antimicrobial lemongrass essential oil—copper ferrite cellulose acetate nanocapsules |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273162/ https://www.ncbi.nlm.nih.gov/pubmed/27104514 http://dx.doi.org/10.3390/molecules21040520 |
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