Evaluation of the Enantiomer Specific Biokinetics and Radiation Doses of [(18)F]Fluspidine—A New Tracer in Clinical Translation for Imaging of σ(1) Receptors

The enantiomers of [(18)F]fluspidine, recently developed for imaging of σ(1) receptors, possess distinct pharmacokinetics facilitating their use in different clinical settings. To support their translational potential, we estimated the human radiation dose of (S)-(−)-[(18)F]fluspidine and (R)-(+)-[(...

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Detalles Bibliográficos
Autores principales: Kranz, Mathias, Sattler, Bernhard, Wüst, Nathanael, Deuther-Conrad, Winnie, Patt, Marianne, Meyer, Philipp M., Fischer, Steffen, Donat, Cornelius K., Wünsch, Bernhard, Hesse, Swen, Steinbach, Jörg, Brust, Peter, Sabri, Osama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273209/
https://www.ncbi.nlm.nih.gov/pubmed/27598110
http://dx.doi.org/10.3390/molecules21091164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273209/
https://www.ncbi.nlm.nih.gov/pubmed/27598110
http://dx.doi.org/10.3390/molecules21091164

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