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Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder worldwide. Currently, the only strategy for palliative treatment of AD is to inhibit acetylcholinesterase (AChE) in order to increase the concentration of acetylcholine in the synaptic cleft. Evidence indicates that AChE also...

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Detalles Bibliográficos
Autores principales:	Mantoani, Susimaire P., Chierrito, Talita P. C., Vilela, Adriana F. L., Cardoso, Carmen L., Martínez, Ana, Carvalho, Ivone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273213/ https://www.ncbi.nlm.nih.gov/pubmed/26861273 http://dx.doi.org/10.3390/molecules21020193

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