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Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer’s Disease

Multitarget drug discovery is one of the hottest topics and most active fields in the search for new molecules against Alzheimer’s disease (AD). Over the last 20 years, many promising multitarget-directed ligands (MTDLs) have been identified and developed at a pre-clinical level. However, how to des...

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Detalles Bibliográficos
Autores principales: Prati, Federica, Cavalli, Andrea, Bolognesi, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273289/
https://www.ncbi.nlm.nih.gov/pubmed/27070562
http://dx.doi.org/10.3390/molecules21040466