Process of Fragment-Based Lead Discovery—A Perspective from NMR

Fragment-based lead discovery (FBLD) has proven fruitful during the past two decades for a variety of targets, even challenging protein–protein interaction (PPI) systems. Nuclear magnetic resonance (NMR) spectroscopy plays a vital role, from initial fragment-based screening to lead generation, becau...

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Detalles Bibliográficos
Autores principales: Ma, Rongsheng, Wang, Pengchao, Wu, Jihui, Ruan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273320/
https://www.ncbi.nlm.nih.gov/pubmed/27438813
http://dx.doi.org/10.3390/molecules21070854

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