Applications of (19)F-NMR in Fragment-Based Drug Discovery

(19)F-NMR has proved to be a valuable tool in fragment-based drug discovery. Its applications include screening libraries of fluorinated fragments, assessing competition among elaborated fragments and identifying the binding poses of promising hits. By observing fluorine in both the ligand and the t...

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Detalles Bibliográficos
Autores principales: Norton, Raymond S., Leung, Eleanor W. W., Chandrashekaran, Indu R., MacRaild, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273323/
https://www.ncbi.nlm.nih.gov/pubmed/27438818
http://dx.doi.org/10.3390/molecules21070860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273323/
https://www.ncbi.nlm.nih.gov/pubmed/27438818
http://dx.doi.org/10.3390/molecules21070860

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