UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion

A rapid and sensitive LC-MS/MS method based on the Triple Quad system has been developed and validated for the determination and pharmacokinetics of taxifolin and its nanodispersion in rat plasma. Taxifolin plasma samples along with butylparaben (internal standard) were pre-treated by liquid-liquid...

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Detalles Bibliográficos
Autores principales: Yang, Chun-Juan, Wang, Zhi-Bin, Mi, Ying-Ying, Gao, Ming-Jie, Lv, Jin-Nan, Meng, Yong-Hai, Yang, Bing-You, Kuang, Hai-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273324/
https://www.ncbi.nlm.nih.gov/pubmed/27089318
http://dx.doi.org/10.3390/molecules21040494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273324/
https://www.ncbi.nlm.nih.gov/pubmed/27089318
http://dx.doi.org/10.3390/molecules21040494

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