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Continuous-Flow Synthesis of Deuterium-Labeled Antidiabetic Chalcones: Studies towards the Selective Deuteration of the Alkynone Core

Flow chemistry-based syntheses of deuterium-labeled analogs of important antidiabetic chalcones were achieved via highly controlled partial C≡C bond deuteration of the corresponding 1,3-diphenylalkynones. The benefits of a scalable continuous process in combination with on-demand electrolytic D(2) g...

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Detalles Bibliográficos
Autores principales:	Ötvös, Sándor B., Hsieh, Chi-Ting, Wu, Yang-Chang, Li, Jih-Heng, Chang, Fang-Rong, Fülöp, Ferenc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273355/ https://www.ncbi.nlm.nih.gov/pubmed/26959006 http://dx.doi.org/10.3390/molecules21030318

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