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Synthesis and Characterization of New 3-(4-Arylpiperazin-1-yl)-2-hydroxypropyl 4-Propoxybenzoates and Their Hydrochloride Salts

Five new 3-(4-arylpiperazin-1-yl)-2-hydroxypropyl 4-propoxybenzoates were designed and synthesized as potential dual antihypertensive agents. The compounds were prepared as free bases and subsequently transformed to hydrochloride salts. The position of protonation of nitrogen atoms in the piperazine...

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Detalles Bibliográficos
Autores principales:	Marvanova, Pavlina, Padrtova, Tereza, Pekarek, Tomas, Brus, Jiri, Czernek, Jiri, Mokry, Petr, Humpa, Otakar, Oravec, Michal, Jampilek, Josef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273361/ https://www.ncbi.nlm.nih.gov/pubmed/27258242 http://dx.doi.org/10.3390/molecules21060707

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