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Predicting the Solubility of Pharmaceutical Cocrystals in Solvent/Anti-Solvent Mixtures

In this work, the solubilities of pharmaceutical cocrystals in solvent/anti-solvent systems were predicted using PC-SAFT in order to increase the efficiency of cocrystal formation processes. Modeling results and experimental data were compared for the cocrystal system nicotinamide/succinic acid (2:1...

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Detalles Bibliográficos
Autores principales: Lange, Linda, Heisel, Stefan, Sadowski, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273375/
https://www.ncbi.nlm.nih.gov/pubmed/27164075
http://dx.doi.org/10.3390/molecules21050593

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