New Deferoxamine Glycoconjugates Produced upon Overexpression of Pathway-Specific Regulatory Gene in the Marine Sponge-Derived Streptomyces albus PVA94-07

Activation of silent biosynthetic gene clusters in Streptomyces bacteria via overexpression of cluster-specific regulatory genes is a promising strategy for the discovery of novel bioactive secondary metabolites. This approach was used in an attempt to activate a cryptic gene cluster in a marine spo...

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Detalles Bibliográficos
Autores principales: Sekurova, Olga N., Pérez-Victoria, Ignacio, Martín, Jesús, Degnes, Kristin F., Sletta, Håvard, Reyes, Fernando, Zotchev, Sergey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273380/
https://www.ncbi.nlm.nih.gov/pubmed/27618884
http://dx.doi.org/10.3390/molecules21091131

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