Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs

The chemical structure of a drug determines its physicochemical properties, further determines its ADME/Tox properties, and ultimately affects its pharmacological activity. Medicinal chemists can regulate the pharmacological activity of drug molecules by modifying their structure. Ring systems and f...

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Detalles Bibliográficos
Autores principales: Mao, Fei, Ni, Wei, Xu, Xiang, Wang, Hui, Wang, Jing, Ji, Min, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273477/
https://www.ncbi.nlm.nih.gov/pubmed/26771590
http://dx.doi.org/10.3390/molecules21010075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273477/
https://www.ncbi.nlm.nih.gov/pubmed/26771590
http://dx.doi.org/10.3390/molecules21010075

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