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Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues

This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main he...

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Detalles Bibliográficos
Autores principales: Driowya, Mohsine, Saber, Aziza, Marzag, Hamid, Demange, Luc, Benhida, Rachid, Bougrin, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273482/
https://www.ncbi.nlm.nih.gov/pubmed/27089315
http://dx.doi.org/10.3390/molecules21040492
Descripción
Sumario:This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main heterocycle types in order of increasing complexity, starting with heterocyclic systems containing one, two and three heteroatoms and their fused analogues. Recent microwave applications are reviewed, with special focus on the chemistry of bioactive compounds. Selected examples from the 2006 to 2015 literature are discussed.