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Bioadhesive Surfactant Systems for Methotrexate Skin Delivery
Methotrexate (MTX) is an immunosuppressive drug for systemic use in the treatment of skin diseases, however, MTX presents a number of side effects, such as hepatotoxicity. To overcome this limitation, this study developed skin MTX delivery surfactant systems, such as a microemulsion (ME) and a liqui...
Autores principales: | Cintra, Giovana Aparecida de Souza, Pinto, Larissa Alvarenga, Calixto, Giovana Maria Fioramonti, Soares, Christiane Pienna, Von Zuben, Eliete de Souza, Scarpa, Maria Virgínia, Gremião, Maria Palmira Daflon, Chorilli, Marlus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273544/ https://www.ncbi.nlm.nih.gov/pubmed/26901183 http://dx.doi.org/10.3390/molecules21020231 |
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